Handheld Tissue Homogenizers
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TGrinder Y50 Handheld Homogenizer
TGrinder Y50 is a handheld tissue homogenizer designed for rapid and flexible sample preparation. Its portable design enables efficient tissue disruption and cell lysis, supporting DNA and RNA extraction across a wide range of sample types. Ideal for both laboratory and field applications, it provides convenient and reliable homogenization for small-scale workflows.
InquireCatalog Number｜Packaging
Mat. No |
Ref. No |
No. of preps |
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OSE-Y50-G |
OSE-Y50-G | 1 set |
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Description
A user-friendly alternative to liquid nitrogen grinding for efficient small-sample homogenization.
The OSE-Y50 Tissue Grinder is a compact and efficient system designed for grinding and homogenizing 1–100 mg of biological samples directly in standard 1.5 mL centrifuge tubes.
Compared with traditional liquid nitrogen grinding methods, it offers a more convenient workflow without the need for cryogenic handling. Its compact size, lightweight design, and low power consumption make it ideal for routine laboratory applications.
The system is widely used for processing animal tissues, including brain, heart, lung, liver, kidney, intestine, lymph node, and muscle, as well as plant tissues such as roots, stems, leaves, flowers, fruits, and seeds.
Equipped with a built-in brushless motor and adjustable speed control, the OSE-Y50 provides flexible and reliable performance for a wide range of sample types.
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Key Features of Y50 Tissue Grinder
Changing the grinding pestle is as simple as replacing a pipette tip, making sample preparation faster, cleaner, and more intuitive.
Aseptic Design for Contamination-Free OperationThe Y50 tissue grinder is equipped with a sterile pestle box, allowing direct insertion during use. This design helps maintain aseptic conditions and reduces the risk of contamination during sample preparation.
Sterile pestle box ensures safe and contamination-free operationCompatible with Multiple Sample TypesBoth plastic and metal grinding pestles are available, making the Y50 suitable for a wide range of biological samples, including plant tissues, animal tissues, and other laboratory materials.
Supports various sample types with different pestlesOne-Press Pestle Removal to Prevent ContaminationThe one-press pestle removal system allows users to unload the pestle safely after grinding. With a single press, the pestle is released directly into the collection box, minimizing user contact and reducing cross-contamination risk.
One-click removal system improves safety and convenience -
Applications of Tissue Grinder Y50
The Y50 tissue grinder is widely used for the grinding and homogenization of various biological samples in molecular biology workflows such as RNA and DNA extraction.
- Animal tissues: brain, heart, lung, liver, kidney, intestine, lymph node, muscle, and other soft tissues
- Plant tissues: roots, stems, leaves, flowers, fruits, and seeds
- Microbial samples: bacteria, fungi, and other microorganisms
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Parameters
Catalog number OSE-Y50-G Product Name TGrinder Y50 Handheld Homogenizer Rotational Speed 0–12000 rpm Rated Voltage 12V power adapter Noise <65 dB Pestle Compatibility 1.5 ml Metal Grinding Pestle (Yes) -
Package Contents
Suit Composition Catalog Number Quantity Handheld Homogenizer OSE-Y50 1 Third generation metal grinding pestle OSE-Y002 2 Pestle removal box OSE-Y003 1 Grinding pestle box (including 40 plastic grinding pestles) OSE-Y004 1 box 
Pestle disassemble box
Pestle box (40 plastic pestles)
TGrinder 3rd Gen Metal Pestle
TGrinder Holder
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Frequently Asked Questions (FAQ)
What is a tissue grinder used for?
A tissue grinder is used to homogenize biological samples such as animal tissues, plant tissues, and microbial samples. It is commonly applied in RNA and DNA extraction workflows and other molecular biology applications.
Can the Y50 tissue grinder replace liquid nitrogen grinding?
Yes. The Y50 provides a convenient alternative to traditional liquid nitrogen grinding methods, eliminating the need for cryogenic handling while maintaining efficient sample homogenization.
What sample types are compatible with the Y50?
The Y50 is suitable for animal tissues (brain, liver, muscle), plant tissues (roots, leaves, seeds), and microbial samples such as bacteria and fungi.
What is the recommended sample size?
The recommended sample size ranges from 1 mg to 100 mg, enabling efficient processing of small-volume samples in 1.5 mL centrifuge tubes.
Does the device support adjustable speed?
Yes. The Y50 is equipped with a brushless motor and adjustable speed control for flexible processing of different sample types.
Is it suitable for RNA and DNA extraction?
Yes. The device is designed for sample preparation in RNA/DNA extraction workflows, providing efficient homogenization and low sample loss.
How does the Y50 reduce contamination risk?
The system features disposable pestles and a one-click removal mechanism to minimize user contact and reduce cross-contamination.
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Precautions and Safety Information
- Operate the grinder intermittently (3–5 seconds per use) to avoid overheating.
- Avoid grinding excessively hard samples to prevent damage.
- Recommended lysis buffer volume: ≤150 μL to prevent splashing.
- Do not immerse the device in liquids to avoid short circuits.
- Avoid contact with strong acids, alkalis, and solvents.
- Ensure proper power connection before use.
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