Dry Bath Incubators

TGrade Bath Shaker

Heat. Cool. Shake. Simplify Your Workflow.
The TGrade Bath Shaker combines precise heating, cooling, and sample mixing in one compact system, making it ideal for cell lysis, enzymatic reactions, protein expression, and other temperature-controlled laboratory workflows.

Catalog Number|Packaging

Mat. No

Ref. No

No. of preps

OSE-DB-03-AM

OSE-DB-03-AM 1 Set

  • Description

    The TGrade Bath Shaker is a programmable heating, cooling, and mixing system designed for applications that require simultaneous incubation and sample agitation. Combining precise temperature control with high-speed shaking, it helps laboratories improve reaction efficiency, sample homogeneity, and workflow productivity.

    Unlike conventional bath shakers that focus only on incubation and mixing, the TGrade Bath Shaker supports high-speed shaking performance suitable for enzyme reactions, cell lysis, protein expression studies, PCR sample preparation, electrophoresis pre-denaturation, and other molecular biology workflows. The powerful mixing capability can also assist bead-based sample disruption and nucleic acid extraction procedures, helping reduce reliance on dedicated homogenizers for certain applications.

    Featuring programmable operation, interchangeable snap-in aluminum blocks, automatic block recognition, and built-in safety protection, the system offers a flexible and reliable solution for modern biotechnology, pharmaceutical, research, and academic laboratories.

  • Why Laboratories Choose This Bath Shaker

    High-Speed Mixing up to 3000 rpm

    Provides stronger mixing performance than many standard bath shakers, making it suitable for cell lysis, nucleic acid extraction, and demanding sample preparation workflows. When used with bead-based disruption media, the instrument can assist sample homogenization and improve preparation efficiency.

    Incubation and Agitation in One System

    Simultaneous heating, cooling, and shaking improve sample homogeneity and reaction efficiency. This integrated design is ideal for enzymatic reactions, protein expression studies, cell lysis, and other temperature-controlled laboratory applications.

    Optimized for Cell Lysis and Sample Preparation

    High-speed shaking combined with precise temperature control makes the system well suited for cell lysis, nucleic acid extraction, enzyme reactions, protein expression studies, and other molecular biology workflows. When used with bead-based disruption media, it can assist sample homogenization and improve preparation efficiency.

    Quick-Change Smart Blocks

    Tool-free snap-in block replacement allows users to switch between different tube formats in seconds without screws or special tools. Automatic block recognition eliminates manual configuration and automatically applies the appropriate operating limits.

    Enhanced Safety for High-Speed Operation

    Integrated over-temperature protection, intelligent speed control, and automatic module recognition help ensure safe and reliable operation during high-speed shaking and routine laboratory workflows.

  • Applications

    Cell Lysis

    Supports bead-assisted cell disruption with simultaneous incubation and agitation, enabling efficient release of intracellular contents for downstream analysis.

    Nucleic Acid Extraction

    Provides controlled temperature and consistent mixing for DNA and RNA extraction workflows, helping improve nucleic acid yield and purity.

    Protein Expression

    Maintains stable incubation conditions and continuous mixing for cell-free protein expression systems, supporting consistent protein yield and activity.

    Enzymatic Reactions

    Ensures uniform temperature distribution and thorough mixing during enzyme digestion, restriction enzyme treatment, and other biochemical reactions, promoting reliable and reproducible results.

    PCR Preparation

    Facilitates reaction setup, reagent mixing, and pre-amplification incubation steps, helping reduce workflow variability and improve PCR consistency.

  • Technical Specifications

    Temperature Setting Range 1–100°C
    Temperature Control Range RT -15°C to 100°C
    Time Setting 1 min – 99 h 59 min 59 sec or Continuous
    Temperature Fluctuation 20°C–45°C ≤ ±0.5°C
    <20°C or >45°C ≤ ±0.8°C
    Temperature Accuracy ≤ ±0.5°C
    Temperature Uniformity 20°C–45°C ≤ ±0.5°C
    <20°C or >45°C ≤ ±0.8°C
    Shaking Speed 300–3000 rpm
    Mixing Orbit 3 mm
    Dimensions 311 × 210 × 145 mm
    Net Weight 5.9 kg
    Power Supply AC110–240 V, 50–60 Hz, 180 W
  • Heating & Cooling Performance

    Block Type 25→95°C RT→10°C 95→25°C
    96 × 0.2 mL ≤12 min ≤12 min ≤12 min
    54 × 0.5 mL ≤12 min ≤12 min ≤12 min
    35 × 1.5 mL ≤12 min ≤12 min ≤14 min
    35 × 2.0 mL ≤12 min ≤12 min ≤14 min
    20 × 15 mL ≤12 min ≤12 min ≤14 min
    32 × 0.2 mL ≤12 min ≤12 min ≤14 min
    8 × 5.0 mL ≤18 min ≤18 min ≤18 min
    8 × 15 mL ≤21 min ≤18 min ≤21 min
    4 × 50 mL ≤21 min ≤18 min ≤21 min
    Ambient temperature: 20–25°C; Relative humidity ≤70%.
  • Interchangeable Aluminum Blocks

    Interchangeable Aluminum Blocks
    Product Name Cat. No. Speed Limit (rpm)
    384-Well Block OSE-DB-A01 300–3000
    96 × 0.2 mL Block OSE-DB-A02 300–2500
    35 × 1.5 mL Block OSE-DB-A03 300–2000
    35 × 2.0 mL Block OSE-DB-A04 300–2000
    12 × 5.0 mL Block OSE-DB-A05 300–1000
    12 × 15 mL Block OSE-DB-A06 300–1000
    4 × 50 mL Block OSE-DB-A07 300–1000
    32 × 0.2 mL + 20 × 1.5 mL Block OSE-DB-A08 300–2000
    Optional aluminum blocks are available for PCR tubes, microcentrifuge tubes, 5 mL, 15 mL and 50 mL tubes to support a wide range of molecular biology workflows.
  • FAQ

    What makes this bath shaker different from standard laboratory shakers?

    The TGrade Bath Shaker combines heating, cooling, and high-speed shaking in a single system. Unlike many conventional laboratory shakers that only provide agitation, it supports temperature-controlled incubation and sample mixing simultaneously, making it suitable for cell lysis, nucleic acid extraction, enzymatic reactions, protein expression, and other molecular biology workflows.

    What applications is the TGrade Bath Shaker designed for?

    The instrument is commonly used for cell lysis, DNA and RNA extraction, enzymatic reactions, cell-free protein expression, PCR preparation, electrophoresis pre-denaturation, reagent mixing, and routine sample incubation in molecular biology and biotechnology laboratories.

    How does high-speed shaking improve sample preparation?

    High-speed shaking improves sample homogenization and mixing efficiency. When used with suitable bead-based disruption media, the system can assist cell disruption and sample processing workflows, helping laboratories perform certain preparation steps more efficiently.

    Can this bath shaker be used for nucleic acid extraction?

    Yes. Controlled temperature conditions combined with high-speed agitation make the instrument suitable for DNA and RNA extraction workflows that require efficient sample mixing and incubation.

    Is the TGrade Bath Shaker suitable for protein expression studies?

    Yes. The instrument provides stable temperature control and continuous mixing, making it suitable for cell-free protein expression systems and other incubation-based protein research applications.

    What types of tubes and blocks are available?

    Multiple interchangeable aluminum blocks are available for PCR tubes, microcentrifuge tubes, 5 mL tubes, 15 mL tubes, 50 mL tubes, and microplate formats, allowing users to adapt the instrument to different laboratory workflows.

    How does the quick-change block system improve workflow efficiency?

    The snap-in block design enables tool-free installation and removal without screws or special tools. This allows users to switch between sample formats quickly while reducing setup time and operational complexity.

    Does the instrument automatically recognize installed blocks?

    Yes. Automatic block recognition identifies the installed module and applies the corresponding operating limits automatically, improving convenience and helping reduce configuration errors.

    What safety features are included?

    The system includes over-temperature protection, intelligent speed management, and automatic block recognition to support safe and reliable operation during both routine incubation and high-speed shaking applications.


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