TGuide S96 Extraction Kits
InquireCatalog Number｜Packaging
Mat. No |
Ref. No |
No. of preps |
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4992997 |
GDP810 | 24 preps |
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Description
The TGuide S96 Circulating DNA Maxi Kit is a magnetic bead-based kit for automated purification of circulating cell-free DNA (cfDNA) from plasma and serum samples. Optimized for use with the TGuide S96 Automated Nucleic Acid Extractor and its large-volume module, the kit supports efficient recovery of low-abundance circulating nucleic acids for liquid biopsy research, molecular diagnostics, and next-generation sequencing (NGS) applications. -
Key Features
Flexible Large-Volume Plasma Processing
Supports purification of circulating cell-free DNA (cfDNA) from up to 2 mL plasma or serum per sample. The TGuide S96 large-volume workflow also enables dual sample plate processing, supporting workflows equivalent to up to 4 mL plasma input for enhanced recovery of low-abundance circulating nucleic acids.
Optimized for cfDNA and Liquid Biopsy Applications
Designed for recovery of circulating cell-free DNA (cfDNA) for liquid biopsy research, biomarker studies, oncology research, and precision medicine applications.
Automated High-Throughput Workflow
Compatible with the TGuide S96 Automated Nucleic Acid Extractor and 24-position large-volume module, helping laboratories improve consistency, reduce hands-on time, and enhance productivity.
NGS-Compatible DNA Quality
Purified cfDNA is suitable for downstream applications including qPCR, molecular diagnostics, biomarker analysis, and next-generation sequencing (NGS).
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Applications & Research Areas
- Plasma and Serum Sample Processing
- Liquid Biopsy Research
- Cell-Free DNA (cfDNA) Analysis
- Cancer Genomics and Oncology Research
- Biomarker Discovery
- Molecular Diagnostics
- NGS Sample Preparation
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FAQ
What is the maximum sample input volume supported by the TGuide S96 Circulating DNA Maxi Kit?
The standard workflow supports purification of circulating nucleic acids from up to 2 mL of plasma or serum per sample. For applications requiring enhanced recovery, the TGuide S96 large-volume workflow can process dual sample plates, supporting workflows equivalent to up to 4 mL plasma input.Is this kit suitable for cell-free DNA (cfDNA) extraction?
Yes. The TGuide S96 Circulating DNA Maxi Kit is specifically designed for automated purification of circulating cell-free DNA (cfDNA) and circulating nucleic acids from plasma and serum samples.Is this kit suitable for liquid biopsy workflows?
Yes. The kit is optimized for recovery of circulating nucleic acids from plasma samples and is suitable for liquid biopsy research, biomarker studies, oncology research, and precision medicine applications.Can purified cfDNA be used for next-generation sequencing (NGS)?
Yes. The purified nucleic acids are suitable for downstream applications including qPCR, molecular diagnostics, biomarker analysis, and next-generation sequencing (NGS) workflows.Can Carrier RNA improve recovery of low-concentration circulating nucleic acids?
Yes. For plasma or serum samples containing low levels of circulating nucleic acids, Carrier RNA can improve nucleic acid recovery efficiency. Carrier RNA is not included in the kit and can be ordered separately as Carrier RNA (Cat. No. RT416-02). It is recommended for liquid biopsy workflows, biomarker studies, and other applications requiring enhanced recovery of low-abundance cell-free DNA (cfDNA).Who typically uses the TGuide S96 Circulating DNA Maxi Kit?
The kit is commonly used by molecular diagnostic laboratories, liquid biopsy researchers, biotechnology companies, genomic service providers, NGS laboratories, translational medicine institutes, and academic research facilities. -
Recommended Accessory
Carrier RNA (Cat. No. RT416-02)
Recommended for recovery enhancement from low-abundance circulating cell-free DNA (cfDNA) samples, including liquid biopsy and low-input plasma workflows.
Experimental Example
High Recovery of Circulating Nucleic Acids from Plasma Samples
Large-volume extraction of circulating nucleic acids from 4 mL plasma samples demonstrated higher recovery and improved consistency compared with alternative commercially available solutions.
Designed for cell-free DNA (cfDNA) analysis, the workflow supports liquid biopsy research, molecular diagnostics, biomarker discovery, and next-generation sequencing (NGS) applications requiring sensitive recovery of low-abundance circulating nucleic acids.
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